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Calmoseptine Ointment is a multipurpose, moisture barrier ointment. It is over-the counter and does not require a prescription to obtain. It was originally developed by a pharmacist as a diaper rash ointment but, over time, has been found to be effective for a number of conditions. Calmoseptine was originally developed for use on infants. Calmoseptine ointment is approved by the FDA for use as a skin protectant drug product. is proud to carry the entire range of this fine brand.