US FDA advises that a potential risk of rare but severe liver injury may be associated with kava-containing dietary supplements. Do not take if you have or have had a liver problems, drink alcohol or take any medications. If you have a medical condition, use under the advice of a health practitioner. Stop use and see a doctor if you develop symptoms that may signal liver problems, including jaundice [yellowing of the skin or whites of the eyes] and brown urine. Other nonspecific symptoms can include nausea, vomiting, light colored stools, unexplained tiredness, weakness, stomach or abdominal pain, and loss of appetite. Not for use by persons under 18 years of age, or by pregnant or breastfeeding women. Not for use with alcoholic beverages. Excessive use, or with products that cause drowsiness, may impair ability to operate a vehicle or heavy equipment. Use only as directed on label. Safety sealed for your protection. Keep bottle capped at all times and store in a cool dry place. Natural separation may occur. This does not affect quality.